Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study

doi:10.5409/wjcp.v15.i2.116098

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Jun 9, 2026; 15(2): 116098
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.116098

Table 1 Comparison between the two studied groups regarding demographic, clinical, and laboratory data, mean ± SD/median (25^th-75^th percentiles)

Parameter	β-thalassemia (n = 40)	Controls (n = 40)	P value
Age (years)	9.24 ± 4.01	7.88 ± 3.82	0.124
Sex (male/female)	22/18	18/22	0.371
Weight (kg)	26.15 ± 9.94	34.40 ± 14.41	0.020
Height (m)	1.20 ± 0.20	1.32 ± 0.25	0.022
BMI (kg/m²)	17.57 ± 2.46	18.72 ± 2.60	0.045
Serum ferritin (ng/mL)	970 (690-1712.5)	79 (59-99)	< 0.001
Hb (g/dL)	8.34 ± 0.96	11.08 ± 0.50	< 0.001
PLT (× 10³/μL)	364.1 ± 18.20	358.4 ± 12.68	0.104
WBCs (× 10³/μL)	10.85 ± 9.68	9.05 ± 1.16	0.376
MCV (fL)	67.8 ± 6.0	80.8 ± 5.2	0.001
MCH (pg)	25.5 ± 2.1	28.7 ± 1.9	0.014
RDW (%)	14.1 ± 1.2	13.8 ± 1.1	0.917
Reticulocytes (%)	6.12 ± 1.5	0.84 ± 0.22	0.001

BMI: Body mass index; Hb: Hemoglobin; PLT: Platelets; WBCs: White blood cells; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; RDW: Red cell distribution width.

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Citation: Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/116098.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.116098

Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098 [PMID: 42220932 DOI: 10.5409/wjcp.v15.i2.116098]

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