Role of soluble alpha-klotho as a novel biomarker for characterizing children with autism spectrum disorder in Kurdistan, Iraq

doi:10.5409/wjcp.v15.i2.112164

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Jun 9, 2026; 15(2): 112164
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.112164

Table 5 Levels of soluble alpha-klotho by age in control and autism spectrum disorder patient groups, mean ± SD

Age (years)	Levels of S-KLα (pg/mL)
Age (years)	Control	Patients with ASD	P value
2-5	171.3 ± 23.5	129.3 ± 12.9	0.001
6-10	125.6 ± 18.1	89.4 ± 8.7	0.001
11-15	104.2 ± 16. 4	73.8 ± 8.4	0.001
Total	133.7 ± 32.4	97.5 ± 19.6	0.001
ANOVA, P value	0.001	0.001

ANOVA: Analysis of variance; ASD: Autism spectrum disorder; S-KLα: Soluble alpha-klotho.

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Citation: Allwsh TA, Kucher DS. Role of soluble alpha-klotho as a novel biomarker for characterizing children with autism spectrum disorder in Kurdistan, Iraq. World J Clin Pediatr 2026; 15(2): 112164
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/112164.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.112164

Allwsh TA, Kucher DS. Role of soluble alpha-klotho as a novel biomarker for characterizing children with autism spectrum disorder in Kurdistan, Iraq. World J Clin Pediatr 2026; 15(2): 112164 [PMID: 42220950 DOI: 10.5409/wjcp.v15.i2.112164]

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