©Author(s) (or their employer(s)) 2026.
World J Clin Pediatr. Mar 9, 2026; 15(1): 114465
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.114465
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.114465
Table 3 Outcomes between randomized study groups within the subgroup of participants with baseline serum 25-hydroxyvitamin D levels < 30 ng/mL (pre-specified vitamin D deficiency/insufficiency subgroup, n = 73), median (interquartile range)/n (%)
| Outcomes | Study group (n = 35) | Comparison group (n = 38) | P value |
| Time from randomization to hospital discharge (hour) | 120 (100-144) | 170 (120-190) | < 0.001a |
| Time from randomization to discontinuation of oxygen supplementation (hour) | 56 (40-68) | 79 (49-90) | 0.012a |
| Time from randomization to discontinuation of parenteral fluids (hour) | 55 (40-75) | 72.5 (48-95) | 0.017a |
| Time from randomization to meeting discharge criteria (hour) | 118 (92-136) | 165 (118-181) | 0.001a |
| Time from hospital admission to discharge (hour) | 126 (106-157) | 177.5 (124-200) | < 0.001a |
| Serum 25 hydroxy vitamin D on day 3 after randomization (ng/mL), mean (SD) | 39.9 (6.56) | 19.8 (6.05) | < 0.001a |
| Serum ionized calcium on day 3 after randomization (mmol/L), mean (SD) | 1.21 (0.12) | 1.16 (0.13) | 0.123 |
| PICU admission | 0 | 5 (13.2) | 0.055 |
| Intubation | 0 | 0 | NA |
| Death | 0 | 0 | NA |
| Nebulized salbutamol therapy | 32 (91.4) | 36 (94.7) | 1.000 |
| Systemic corticosteroids | 9 (25.7) | 6 (15.8) | 0.294 |
- Citation: Abdelkreem E, Labeeb YS, Mohamed MA. Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial. World J Clin Pediatr 2026; 15(1): 114465
- URL: https://www.wjgnet.com/2219-2808/full/v15/i1/114465.htm
- DOI: https://dx.doi.org/10.5409/wjcp.v15.i1.114465