Functional constipation in Thai infants and toddlers: The role of genetic-gut-brain interaction and fiber supplementation

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Mar 9, 2026; 15(1): 111828
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.111828

Table 1 Demographic data and family status, n (%)

	Total (n = 1874)	Constipated (n = 302)	Non-constipated (n = 1572)	P value
Area of residence				0.206
Central	774 (41.3)	132 (43.7)	642 (40.8)
Eastern	207 (11)	34 (11.3)	173 (11)
Northern	363 (19.4)	59 (19.5)	304 (19.3)
Northeastern	326 (17.4)	56 (18.5)	270 (17.2)
Southern	204 (10.9)	21 (7)	183 (11.6)
Male	1003 (53.5)	147 (48.7)	856 (54.5)	0.065
Age (months)	20.3 ± 11.4	25.6 ± 11.2	19.3 ± 11.2	< 0.001^a
6-12	550 (29.3)	32 (10.6)	518 (33)	< 0.001^a
≥ 12	1324 (70.7)	270 (89.4)	1054 (67)
Nutritional status				0.161
Obese	24 (1.3)	8 (2.6)	16 (1)
Overweight	89 (4.7)	12 (4)	77 (4.9)
Normal	1671 (89.2)	265 (87.7)	1406 (89.4)
Underweight	82 (4.4)	15 (5)	67 (4.3)
Malnutrition	8 (0.4)	2 (0.7)	6 (0.4)
Family number	4.75 ± 1.74	4.84 ± 1.86	4.73 ± 1.71	0.313
Single family	904 (48.3)	154 (51)	750 (47.7)	0.3
Main caregiver: Mother	1190 (63.5)	206 (68.2)	984 (62.6)	0.063
Main caregiver educational level				0.316
Lower than mandatory education (below high school)	436 (23.3)	77 (25.5)	359 (22.8)
At least mandatory education (at least high school)	1438 (76.7)	225 (74.5)	1213 (77.2)
Family status				0.76
Together	1740 (92.8)	283 (93.7)	1457 (92.7)
Separated	91 (4.9)	12 (4)	79 (5)
Divorced	32 (1.7)	6 (2)	26 (1.7)
Widowed	11 (0.6)	1 (0.3)	10 (0.6)
Family income				0.493
Low income (< 30000 bahts/month)	718 (38.5)	127 (40.2)	591 (38.1)	0.493
Family debt	1187 (63.4)	210 (69.5)	977 (62.2)	0.015^a
First degree relative with a history of constipation	323 (17.2)	98 (32.5)	225 (14.3)	< 0.001^a
Family history of atopy	634 (33.8)	116 (38.4)	518 (33)	0.066
Child history of atopy	220 (11.7)	48 (15.9)	172 (10.9)	0.014^a

^aP < 0.05.

Citation: Chatpermporn K, Ngoenmak T, Charoenwat B, Chanpong A, Sriphongphankul H, Hanpitakpong N, Sintusek P. Functional constipation in Thai infants and toddlers: The role of genetic-gut-brain interaction and fiber supplementation. World J Clin Pediatr 2026; 15(1): 111828
URL: https://www.wjgnet.com/2219-2808/full/v15/i1/111828.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i1.111828

Chatpermporn K, Ngoenmak T, Charoenwat B, Chanpong A, Sriphongphankul H, Hanpitakpong N, Sintusek P. Functional constipation in Thai infants and toddlers: The role of genetic-gut-brain interaction and fiber supplementation. World J Clin Pediatr 2026; 15(1): 111828 [PMID: 41884022 DOI: 10.5409/wjcp.v15.i1.111828]

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