Early inotropic support without fluid bolus vs standard resuscitation in pediatric septic shock: A randomized controlled trial

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Mar 9, 2026; 15(1): 109864
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.109864

Table 4 Multiregression analysis of various parameters to predict the final outcome

	Unstandardized B	t	Sig
Constant	1.609	2.775	0.009
Intervention group	-0.790	-0.509	0.614
Underlying comorbidity	-0.207	-1.375	0.180
Diastolic shock index	-0.065	-1.636	0.112
Ventilatory requirement	0.082	0.813	0.423
Compensated vs hypotensive shock	-0.150	-0.981	0.335
Signs of fluid overload	-0.130	-0.840	0.408
Maximum VIS score	0.003	2.074	0.047
pSOFA-L score	0.047	2.349	0.026

VIS: Vasoactive inotropic support; pSOFA-L score: Pediatric Sequential Organ Failure Assessment- Lactate score.

Citation: Keshri S, Goel AK, Garg AK, Anand V, Rathia SK, Yusuf S. Early inotropic support without fluid bolus vs standard resuscitation in pediatric septic shock: A randomized controlled trial. World J Clin Pediatr 2026; 15(1): 109864
URL: https://www.wjgnet.com/2219-2808/full/v15/i1/109864.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i1.109864

Keshri S, Goel AK, Garg AK, Anand V, Rathia SK, Yusuf S. Early inotropic support without fluid bolus vs standard resuscitation in pediatric septic shock: A randomized controlled trial. World J Clin Pediatr 2026; 15(1): 109864 [PMID: 41884053 DOI: 10.5409/wjcp.v15.i1.109864]

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