Giant coronary aneurysms in children with Kawasaki disease and major cardiac complications and dynamic follow-up

Table 6 Follow-up of patients with Kawasaki disease and giant coronary aneurysms (9 patients, subgroup 1a)

ID, sex, age at KD onset	CA	CA, Z-score, SD				Clinical events
		At onset	After 3 months	After 6 months	After 1 year
1, M, 5 months	LCA	12.80 multiple aneurysms	9.80	NA	4.80	Giant CA of AIVA and RCA, subtotal thrombosis of AIVA, acute myocardial infarction, coronary bypass grafting. After 1-year complete recanalization of thrombosis. Regression of LCA aneurysm to ectasia, recanalization of AIVA, and shunt thrombosis. After 15 years normal LCA and RCA diameter
	RCA	13.70 multiple aneurysms	4.20	NA	2.90	Regression to ectasia, normal diameter after 15 years
2, M, 9 months	LCA	11.08	8.80	8.51	6.74	Partial regression, complete regression after 3 years
	RCA	10.44	8.39	6.83	5.93	Partial regression, normal diameter after 3 years
3, M, 3 months	LCA	10.80	5.41	6.69	3.56	Slow wave-like regression to ectasia after 5 years
	RCA	6.80	5.73	7.26	4.71	Slow wave-like regression to ectasia after 5 years
4, M, 8 years	LCA	11.20	NA	NA	-0.44	Complete regression after 1 year
	RCA	8.43	NA	NA	3.07	Slow regression to ectasia in 1-year, complete regression after 4 years
5, M, 3 years	LCA	2.12	0.91	0.24	11.59	Moderate dilatation in the first episode of KD with regression and formation of giant CA in the recurrence of KD. Complete regression after 4 years
	RCA	2.22	0.81	0.65	1.29	In the first episode of KD, moderate coronary dilatation with further complete regression
6, M, 3 months	LCA	1.74	NA	6.8	3.59	Coronary dilatation after 6 months with progression to CA and partial regression to ectasia after 1 year
	RCA	26.50	NA	1.70	4.88	Complete regression did not occur after 1 year of partial regression of giant CA to ectasia; complete regression did not occur
7, F, 5 years	LCA	10.90	18.00	NA	0.11	Giant CA with diameter increased after 3 months and complete regression after 1 year from the onset of KD
	RCA	1.37	1.06	NA	0.06	Not involved
8, F, 8 months	LCA	12.90	NA	12.70	12.21	Giant aneurysm after 1 year without change, complete regression after 5 years
	RCA	-0.51	NA	-0.58	-0.36	Not involved
9, F, 2 years	LCA	14.30	NA	NA	16.36	Giant CA with diameter increased after 1-year, partial regression to large aneurysm (Z-score < 10) after 4 years
	RCA	0.50	NA	NA	0.72	Not involved

Numbering corresponds to Table 3. AIVA: Anterior interventricular artery; СA: Coronary artery; F: Female; KD: Kawasaki disease; LCA: Left coronary artery; M: Male; NA: Not available; RCA: Right coronary artery; SD: Standard deviation.