Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges

doi:10.5409/wjcp.v14.i4.107974

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Dec 9, 2025; 14(4): 107974
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.107974

Table 2 Common pathogens in neonatal and pediatric sepsis by region and comorbidity[15,16]

Region/Condition	Neonatal sepsis - common pathogens	Pediatric sepsis - common pathogens
Developed countries	Group B Streptococcus, Escherichia coli, Listeria spp.	Streptococcus pneumoniae, Neisseria meningitidis, MRSA
Developing countries	Klebsiella pneumoniae, Acinetobacter baumannii, Escherichia coli	Salmonella spp., Staphylococcus aureus, Pseudomonas aeruginosa
NICU/PICU settings	MDR Klebsiella, Candida albicans, Enterococcus spp.	Acinetobacter, Stenotrophomonas maltophilia
Immunocompromised children	Pseudomonas aeruginosa, Candida parapsilosis	Nocardia, Fusarium, Aspergillus, MDR GNB

GNB: Gram-negative bacilli; MDR: Multidrug-resistant; MRSA: Methicillin-resistant Staphylococcus aureus; NICU: Neonatal intensive care units; PICU: Pediatric intensive care unit.

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Citation: Nagoba BS, Dhotre SV, Sonar MN, Mumbre SS, Gavkare AM, Dhotre PS. Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges. World J Clin Pediatr 2025; 14(4): 107974
URL: https://www.wjgnet.com/2219-2808/full/v14/i4/107974.htm
DOI: https://dx.doi.org/10.5409/wjcp.v14.i4.107974

Nagoba BS, Dhotre SV, Sonar MN, Mumbre SS, Gavkare AM, Dhotre PS. Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges. World J Clin Pediatr 2025; 14(4): 107974 [PMID: 41255658 DOI: 10.5409/wjcp.v14.i4.107974]

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