Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Pediatr. Sep 9, 2025; 14(3): 106778
Published online Sep 9, 2025. doi: 10.5409/wjcp.v14.i3.106778
Table 5 Summary of studies on behavioral and sensory adaptation techniques for managing dental disorders in children with autism spectrum disorder using the PICO framework
Ref.
Population
Intervention
Comparison
Outcome
Study design
Key findings
Study quality rating
Marion et al[42], 2016Children with ASD (n = 40)Use of dental stories to prepare for dental visitsNo preparatory aids64% of caregivers found dental stories useful for their child’s preparationSurvey-based studyCaregivers preferred individualized story formats to match child’s comprehension levelHigh quality
Star et al[43], 2023Children with ASD (n = 52)Dental desensitization program (task analysis approach)Standard preventive visitsIncreased comfort and step completion in dental visitsProspective cohort studyChildren with expressive and receptive language skills benefited mostModerate quality
Cai et al[44], 2022Parents of children with ASD (n = 13)Parent-reported effectiveness of desensitizationNo structured desensitizationReduced anxiety and improved treatment acceptanceQualitative studyBarriers include financial burden and frequent appointmentsLow quality
Yost et al[45], 2019Children with ASD (n = 138)Two-year follow-up on desensitization treatmentInitial exam acceptance only92% retained examination skills, 83% accepted toothbrush prophylaxisRetrospective case seriesSensory-invasive skills (radiographs) were acquired less frequentlyModerate quality
Myhren et al[46], 2023Children with ASD (n = 17)Individualized dental habituation programStandard dental exams82% completed dental exams, increased compliance with mirror and probeMixed-methods studyCollaboration with school personnel improved outcomesModerate quality
Junnarkar et al[47], 2022Occupational & speech therapistsRole of therapists in dental careNo therapist involvementIdentified barriers to oral care and potential solutionsQualitative studyTherapists play a key role in early intervention and pre-visit preparationModerate quality
Luscre and Center[48], 1996Children with ASD (n = 3)Desensitization with anxiety-reducing stimuliNo desensitizationIncreased step completion in a clinical settingExperimental studySystematic desensitization reduces dental fearModerate quality
Mah and Tsang[34], 2016Children with ASD (n = 14)Visual schedule system during dental visitsTell-show-do methodFaster task completion, reduced distressRCTVisual schedules enhanced cooperation and reduced anxietyHigh quality
Hernandez and Ikkanda[49], 2011Children with ASDABA in dental careStandard behavior managementImproved cooperation with dental proceduresLiterature reviewABA principles effectively modify problematic dental behaviorsLow quality
Uliana et al[42], 2024Children with ASD (n = 61)Impact of behavioral factors on caries prevalenceCooperative childrenHigher support needs linked to increased caries ratesCross-sectional studyPoor mealtime behavior and dental noncompliance increased caries riskLow quality