Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Pediatr. Sep 9, 2025; 14(3): 105290
Published online Sep 9, 2025. doi: 10.5409/wjcp.v14.i3.105290
Table 2 Comparison between the different patterns of symptom onset and progression in pediatric functional neurological disorder
Pattern
Onset characteristics
Progression
Common triggers
Prognosis
Sudden onsetAbrupt appearance of symptoms. Often after a significant stressorSymptoms can be severe from the outset. May resolve quickly or persistAcute psychological stress. Traumatic eventsMay resolve rapidly with early intervention. Can persist if underlying issues are not addressed
Gradual onsetSymptoms develop slowly over time. Initially mild and subtleSymptoms progressively worsen. May become more disabling over timeAccumulation of stressors. Unresolved psychological issuesDelayed diagnosis is common. Symptoms may become chronic without treatment
Relapsing-remittingFluctuating symptoms. Periods of remission interspersed with exacerbationsSymptoms wax and wane. Exacerbations linked to stressFluctuating stress levels. Environmental changesRequires ongoing management. Stress management can reduce relapses
Persistent chronicStable but persistent symptoms. Long-lasting with little fluctuationSymptoms remain consistent over time. Can lead to significant disabilityLong-standing psychological or emotional issuesChallenging to treat. Multidisciplinary approach needed for improvement