MicroRNA-320а as a novel biomarker at preclinical stage of necrotizing enterocolitis in term neonates with congenital heart defects

Table 3 Laboratory parameters of term newborns with critical congenital heart defects before and after cardiac surgery

Laboratory parameters		No-NEC (n = 14)	P value	NEC (n = 9)	P value	P value between groups
Hemoglobin (g/L)	Before	155.0 (141.0-175.5)	0.003	159.0 (128.5-180.0)	0.050	0.847
	After	129.5 (113.0-146.0)		120.0(109.0-143.0)		0.705
Erythrocytes (× 1012/L)	Before	4.68 (4.24-5.00)	0.110	4.64 (3.70-5.15)	0.208	0.787
	After	4.11 (3.74-4.64)		3.91 (3.55-4.87)		0.900
Platelets (× 109/L)	Before	345.5 (280.0-375.5)	0.583	291.0 (243.5-424.0)	0.674	0.758
	After	372.0 (227.0-501.0)		298.0 (232.0-421.0)		0.244
Leukocytes (× 109/L)	Before	13.65 (11.20-15.65)	0.724	11.45 (8.95-15.35)	0.327	0.375
	After	12.70 (11.70-15.00)		11.70 (10.40-19.40)		0.801
Band neutrophils (%)	Before	1.0 (1.0-1.5)	0.624	1.5 (1.0-2.0)	0.686	0.512
	After	1.0 (0.0-3.0)		1.0 (1.0-2.0)		0.395
Segmented neutrophils (%)	Before	40.0 (35.5-49.5)	0.023	42.5 (40.0-58.0)	0.779	0.217
	After	60.0 (52.0-65.0)		48.0 (44.0-58.0)		0.078
Eosinophils (%)	Before	5.0 (3.0-6.5)	0.103	4.5 (3.6-6.0)	0.447	0.969
	After	3.0 (1.0-5.0)		6.0 (0.0-10.0)		0.314
Lymphocytes (%)	Before	40.0 (36.0-44.5)	0.045	37.0 (25.5-40.5)	0.484	0.247
	After	20.5 (15.0-30.0)		25.0 (16.0-30.0)		0.825
C-reactive protein (mg/L)	Before	7.0 (4.0-10.5)	0.034	1.5 (0.8-5.0)	0.463	0.101
	After	8.2 (5.0-15.0)		6.1 (3.0-18.0)		0.550

Data are median (interquartile range). NEC: Necrotizing enterocolitis.