Prematurity is a risk factor of disorders of gut-brain interaction in adults: A case-control study

Table 1 General characteristics of the adults born preterm (Health of Adults Born Preterm Investigation cohort)

Characteristics of adults born prematurely		n (interquartile)	Percentage (%)
Social demographics	Men/women median age (years)	24/55, 27 (24; 29)	30/70
Neonatal factors	Gestational age (WG): 24; 25; 26; 27; 28 and 29	4; 16; 10; 20; 22 and 7	5; 20; 13; 25; 28 and 9
	Median birthweight (grams)	920 (768; 1116)
	Antenatal steroids	34 (MD = 9)	43
	Median duration of mechanical ventilation (days)	26 (4; 44) (MD = 10)
	Oxygen support at 36 WG	24 (MD = 9)	30
	Median total parenteral nutrition (days)	29 (16; 41) (MD = 13)
	Median hospitalization length (days)	78 (66; 106) (MD = 7)
	Sepsis event	13 (MD = 8)	17
	Necrotizing enterocolitis	2 (MD = 8)	3
	C-section	38 (MD = 8)	48
	Chorioamniotitis	8 (MD = 23)	10
	Post natal steroids	19 (MD = 11)	24
	Intraventricular Hemorrage	19 (MD = 8)	24
	Surgery	14 (MD = 18)	18
	Small for gestational age (ultrasound)	39 (MD = 17)	49
Patient-Reported Outcomes Measurement Information System-29 items questionnaire	Median physical function score	20 (19; 20)
	Median anxiety score	8 (5; 11)
	Median depression score	6 (4; 10)
	Median fatigue score	9 (7; 11)
	Median sleep disturbance score	10 (8; 12)
	Median ability to participate in social roles and activities score	18 (14; 20)
	Median pain interference score	4 (4; 5)
	Median pain intensity	1 (0; 3)
Patient Health Questionnaire-9 items-D score (depression)	Absent	40	51
	Mild	23	29
	Moderate to severe	14	18
Generalized Anxiety Disorder-7 items-D (anxiety)	Minimal	50	63
	Mild	18	23
	Moderate to severe	9	12

MD: Missing data; WG: Weeks of gestation.