Genetic variation features of neonatal hyperbilirubinemia caused by inherited diseases

Table 4 Gene mutation analysis between high and low total serum bilirubin groups

	Hyperbilirubinemia
Mutation	Total serum bilirubin ≥ 342 µmol/L	Total serum bilirubin < 342 μmol/L	P value
Uridine 5'-diphospho-glucuronosyltransferase 1A1
G/A	32	11	0.32
C/T	4	3
T/G	1	1
Na+/taurocholate cotransporting polypeptide Ntcp
C/T	6	7	NA
Heterozygous 851del4 mutation
C.852_855delTATG	2	3	0.57
C.1638_1660dup	0	1
G/A	0	1
Adenosine triphosphatase 7B
G/T	1	0	0.26
A/C	1	0
G/A	0	1
C/T	0	1
Glucose-6-phosphate dehydrogenase
G/T	1	2	0.32
G/A	1	0
A/G	0	1