Treatment of central sleep apnea in patients with heart failure: Now and future

Table 4 Long term randomized control trial investigating the effects of adaptive servo ventilation treatment on cardiovascular outcomes in heart failure patients with central sleep apnea

Author, year	Duration	n	Design	Findings
Cowie, 2015[15] (SERVE-HF trial)	31 mo (median)	1325	mv-ASV vs CSA-control	All-cause and cardiovascular mortality were both increased in ASV group

RCT: Randomized control trial; ASV: Adaptive servo ventilation; HF: Heart failure; CSA: Central sleep apnea; mv-ASV: Minute volume of ventilation-targeted ASV.