Role of chronic obstructive pulmonary disease in lung cancer pathogenesis

Table 1 Examples of genetic regions relevant to increased susceptibility to both chronic obstructive pulmonary disease and lung cancer

Chromosomal region	Possible gene(s)	Ref.
2q	GSS	[23]
4q31	HHIP, GYPA	[21]
5q33	HTR4, ADAM19	[21]
6p	GCLCL	[23]
6q	SMOC2	[22,24,25]
10q	GSTO2	[23]
11p	MMP1, MMP12, RRM1	[23,26]
12p	GSTM1	[27,28]
15q25	CHRNA3-5, IREB2	[21]
19q	ERCC1	[23]