Aspirin cures erythromelalgia and cerebrovascular disturbances in JAK2-thrombocythemia through platelet-cycloxygenase inhibition

Table 2 Localization of erythromelalgia in feet/toes vs fingers and skin, and the presence of peripheral gangrene and history of acute coronary syndrome or migraine-like cerebral ischemic attacks, and time lap between first manifestations of erythromelalgia and diagnosis of thrombocythemia in essential thrombocythemia (n = 11) and polycythemia vera (n = 13)

Patient	Diagnosis	Feet toes	Fingers	Skin	PG	ACS	MIAs	Time lap (mo)
1	ET	Bilateral		Present	Yes	Yes	Yes	45
2	ET	Bilateral			Yes		Yes	154
3	ET							60
4	ET	Unilateral			Yes	Yes		12
5	ET	Unilateral	Unilateral	Present	Yes			4
6	ET					Yes	Yes	20
7	ET						Yes	60
8	ET							30
9	ET	Bilateral			Yes			20
10	ET	Bilateral	Bilateral	Present	Yes			30
11	ET	Bilateral		Present				30
12	PV	Unilateral						24
13	PV	Unilataral						3
14	PV	Bilataral						0
15	PV		Unilateral	Present	Yes	Yes		36
16	PV	Bilateral					Yes	48
17	PV	Unilateral						1
18	PV	Bilateral					Yes	18
19	PV		Bilateral					2
20	PV	Bilataral			Yes			24
21	PV	Unilateral						4
22	PV	Unilateral		Present				3
23	PV	Unilateral	Unilateral					24
24	PV		Unilateral					6

PG: Peripheral gangrene; ACS: Acute coronary syndrome; ET: Essential thrombocythemia; PV: Polycythemia vera; MIAs: Migraine-like cerebral ischemic attacks.