Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Hematol. Aug 6, 2014; 3(3): 49-70
Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.49
Table 6 Children oncology group approach to relapsed acute lymphoblastic leukaemia[29]
RelapseSiteTimeMRD
B-lineageMarrowEarlyChemotherapy vs chemotherapy plus novel agentsNegativeSCT
PositiveBridging study before HSCT
LateChemotherapy vs chemotherapy plus novel agentsNegativeContinuation therapy
PositiveSCT
IEMEarlyChemotherapy vs chemotherapy plus novel agentsAnySCT
LateChemotherapy vs chemotherapy plus novel agentsNegativeContinuation therapy
PositiveSCT
T-lineageMarrowEarlyChemotherapy vs chemotherapy plus novel agentsNegativeSCT
LatePositiveBridging study before HSCT
IEMEarlyChemotherapy vs chemotherapy plus novel agents
LateAnySCT