PVSG and WHO vs European Clinical, Molecular and Pathological Criteria for prefibrotic myeloproliferative neoplasms

Figure 5 Forty-three-year-old female with positive polycythemia vera (platelets 405 × 10⁹/L, low serum erythropoietin, leukocyte alkaline phosphatase score 283, hematocrit 0. 52, erythrocytes 6.1 × 10¹²/L, increased red cell mass) with a diagnostic essential thrombocythemia/polycythemia vera bone marrow picture. Such essential thrombocythemia (ET)/polycythemia vera (PV) pictures are regularly seen in prodromal PV and overt PV. A-D: JAK2^V617F positive early stage PV with a ET/PV bone marrow histology with loose clusters of pleomorphic megakaryocytes.