Review
Copyright ©2013 Baishideng.
World J Hematol. Aug 6, 2013; 2(3): 71-88
Published online Aug 6, 2013. doi: 10.5315/wjh.v2.i3.71
Table 1 Blood and bone marrow features in one prospective study of Thrombocythemia Vera Study Group-defined essential thrombocythemia and one retrospective study of Polycythemia Vera Study Group defined essential thrombocythemia at platelet counts above the upper limit of normal
Ref.Michielset al[11]Lengfelderet al[30]
Type of studyProspective 1975-1985Retrospective 1975-1995
Diagnosis ETTVSG criteriaPVSG criteria
Inclusion criterionETETTentative diagnosis
Platelet count × 109/L> 400> 350WHO-ECMP
Number of ET patients30143
Platelets × 109/L range420-1500< 350-> 000
Below 60013%29%Early latent ET
Between 600-100054%45%Fits with ET
Above 100033%26%Fits with ET
Leukocytes
Above 12 × 109/L10%51%
Hemoglobin
Below 16 g/dL-80%
Below 17 g/dL-100%
Above 16 g/dL-20%Fits with PV
Splenomegaly
No63%56%
Yes37%44%
Spleen size on echogram (cm)
n < 12/12-15/> 152019/8/3-
Bone marrow biopsy
Normal cellularity17 (57%)52%Fits with true ET
Increased cellularity13 (43%)60%
Increased erythropiesis13 (43%)17%Fits with early PV
Increased granulopiesis045%Fits with CMGM
MyelofibrosisNoNo