Review
Copyright ©The Author(s) 2016.
World J Dermatol. May 2, 2016; 5(2): 72-83
Published online May 2, 2016. doi: 10.5314/wjd.v5.i2.72
Table 1 Events downstream of P2X7 receptor activation
RONS formation
Shedding of CD23, CD27, CD62L and E-cadherin
Up-regulation of CD80 and CD86 expression
PGE-2 synthesis and release
IL-1β and IL-18 maturation and release
IL-6 release
IL-2 and IL-17 synthesis and release
VEGF release
Killing of intracellular pathogens
Cell death