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Copyright ©The Author(s) 2015.
World J Dermatol. May 2, 2015; 4(2): 103-107
Published online May 2, 2015. doi: 10.5314/wjd.v4.i2.103
Table 1 Clinical features and three phase treatment of nicolau syndrome
PhaseClinical featuresTreatment
InitialIntense painAnalgesics
ErythemaSystemic antibiotics1
Radiating painNo ice pack
Faintness, syncope
AcuteLivedoid plaqueSystemic steroid
Violaceous patchAnticoagulant agent
Non-necrotic
NecroticNecrotic indurated plaqueSurgical debridement
Ulceration with necrosisPlastic surgery