Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines

Figure 3 Osteonecrosis of the femoral head treated with prolonged delivery of 500 μg of vascular endothelial growth factor through a pump (t-VEGFpump-μ group). At 12 wk postoperatively, a well-formed trabecular network is visible, with slightly thickened lamellar trabeculae, and normal marrow cells and adipose tissue (A) in between. A: Few trabeculae are covered by newly formed bone (vT), the presence of nuclei in lacunae is noticed (Obj. × 10, H and E); B: New bone (vT) formation is observed on the surface of some trabeculae (Obj. × 10, TB).