Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines

Figure 2 Osteonecrosis of the femoral head treated with a single injection of 500 μg vascular endothelial growth factor (t-VEGFμ group); specimen retrieved 12 wk postoperatively. A well-formed cancellous bone network with thickened lamellar trabeculae is visible, while the in between spaces are filled with normal marrow cells (M). A: Newly formed (vT) were noticed on the surface of the trabeculae (T) (Obj. × 10, H and E). B: Almost all trabeculae’s (T) surface is covered by newly (vT) formed bone (Obj. × 10, TB).