Total joint replacement in inhibitor-positive haemophilia: Long-term outcome analysis in fifteen patients

Table 2 Main surgical operations in the patients (C-F) with the high historical inhibitor titre

Patient and operations (model)	Replacement therapy	Primary haemostatic outcome	Surgical outcome ROM/pain
C
TKR bilateral (hinge + posterior stabilised)	pdFVIII → aPCC	Poor	Fair
THR (uncemented)	rFVIII	Good	Good
D
TKR bilateral (reconstructive)	aPCC → rFVIIa	Fair	Fair
E
TKR (posterior stabilized)	aPCC → rFVIIa	Poor	Good
F
Glenohumeral hemiarthroplasty	rFVIII	Good	Good

ROM: Range of motion; TKR: Total knee replacement; THR: Total hip replacement; aPCC: Activated prothrombinase complex concentrate.