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Copyright ©2014 Baishideng Publishing Group Inc.
World J Orthop. Sep 18, 2014; 5(4): 516-536
Published online Sep 18, 2014. doi: 10.5312/wjo.v5.i4.516
Table 2 The examined interleukin and interleukin receptor gene polymorphisms that are associated with rheumatoid arthritis
GenePolymorphismPopulationRef.
IL-1Brs16944Algerian, British, Turkish[34,35,40]
rs1143623British[35]
rs1143634Algerian, Asian, Turkish[34,40-42]
IL1-RNrs419598Black South Africans[36]
IL-2/IL-21rs907715Australasian[72]
rs6822844Australasian, Dutch[65,72]
rs17388568Australasian[72]
IL-2RArs2104286Dutch[64]
IL-4rs2243250Egyptian, Polish[51,52]
IL-4Rrs1801275African American, Egyptian[54,55]
rs1805010African American, Egyptian[54,55]
IL-6rs1800795Iranian, United Kingdom, Spain, Spanish, Turkish[34,114,116, 117,122]
rs1800796Han Chinese, Taiwan, Turkish[34,43,47,118]
IL-8rs112664Taiwan[118]
rs2227306Caucasian[137]
IL-10rs1800871Malaysian, Polish[80,81]
rs1800872Chinese, Malaysian, Polish[80-82]
rs1800896Malaysian, Polish[80,81]
IL-15rs2322182North European[59]
rs4371699North European[59]
rs6821171North European[59]
rs7665842North European[59]
rs7667746North European[59]
IL-17Ars1974226Japanese[136]
rs2275913Norwegian[135]
rs3748067Japanese[136]
rs3804513Japanese[136]
IL-17Frs763780Polish[134]
rs2397084Polish[134]
IL-18rs187238Chinese, Egyptian[46,47]
rs549908Taiwan[48]
rs360718Japanese[49]
rs360722Japanese[49]
rs1946518Chinese, Egyptian, Japanese[46,47,49]
IL-23Rrs1004819European, New Zealand, Spanish[97,100,106]
rs1343151European, New Zealand, Spanish[97,100,106]
rs1495965Spanish[97]
rs2201841European, New Zealand, Hungarian[96,97,100,106]
rs7517847European, New Zealand, Spanish[97,100,106]
rs7530511Caucasian[98]
rs10889677Hungarian[96]
rs11209026European, Caucasian, New Zealand[98,100,106]
rs11209032Spanish[97]
rs10489629Europan, New Zealand, Spanish[97,100,106]