Missouri osteochondral preservation system transplantation: Outcome scores from 24 months to 60+ months

doi:10.5312/wjo.114039

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. Sep 18, 2026; 17(9): 114039
Published online Sep 18, 2026. doi: 10.5312/wjo.114039

Table 4 Patient-reported outcome measures (mean ± SD, P value)

	PreOp (n = 29)	3-6 months (n = 18)	6-12 months (n = 20)	12-24 months (n = 18)	24-36 months (n = 11)	36-60 months (n = 15)	60+ months (n = 11)
Pain frequency	8.69 ± 1.98	4.6 ± 2.8, P < 0.001¹	4.7 ± 2.9, P < 0.001¹	4.2 ± 3.0, P < 0.001¹	4.1 ± 2.5, P < 0.001¹	3.8 ± 2.8, P < 0.001¹	3.5 ± 3.2, P < 0.001¹
Pain severity	5.36 ± 3.16	4.5 ± 2.8, P = 0.295	4.6 ± 2.2, P = 0.083	5.0 ± 2.1, P = 0.195	5.2 ± 2.1, P = 0.371	4.3 ± 2.8, P = 0.018¹	3.8 ± 2.8, P = 0.042¹
IKDC function	32.18 ± 16.83	48 ± 15.9, P = 0.004¹	53.5 ± 18.0, P < 0.001¹	58.7 ± 21.7, P < 0.001¹	60.1 ± 20.6, P = 0.002¹	62.1 ± 20.5, P < 0.001¹	64.4 ± 22.1, P < 0.001¹
Lysholm	39.78 ± 19.3	62.3 ± 19.4, P < 0.001¹	64.3 ± 23.7, P < 0.001¹	72.6 ± 22.9, P < 0.001¹	68.8 ± 21.3, P < 0.001¹	65.3 ± 22.0, P < 0.001¹	66.6 ± 21.8, P < 0.001¹
KOOS pain score	47.41 ± 22.33	68.7 ± 19.6, P = 0.001¹	71.6 ± 20.7, P < 0.001¹	74.0 ± 22.7, P < 0.001¹	80.7 ± 20.5, P < 0.001¹	74.6 ± 20.5, P < 0.001¹	76.0 ± 18.4, P < 0.001¹
KOOS symptom	48.58 ± 24.17	64.6 ± 16.7, P = 0.010¹	70.1 ± 18.1, P < 0.001¹	75.1 ± 19.5, P < 0.001¹	78.4 ± 18.5, P < 0.001¹	74.0 ± 19.6, P = 0.001¹	75.0 ± 18.3, P < 0.001¹
KOOS ADL	54.77 ± 23.60	77.3 ± 18.8, P = 0.005¹	81.0 ± 18.9, P < 0.001¹	81.6 ± 19.8, P < 0.001¹	86.7 ± 20.1, P < 0.001¹	81.1 ± 15.9, P < 0.001¹	84.2 ± 15.4, P < 0.001¹
KOOS sport	25.89 ± 23.02	44.0 ± 25.3, P = 0.077	52.3 ± 25.4, P < 0.001¹	49.4 ± 24.1, P = 0.001¹	56.7 ± 26.7, P = 0.005¹	55.7 ± 31.2, P = 0.001¹	55.0 ± 32.4, P = 0.001¹
KOOS QOL	21.55 ± 15.99	41.4 ± 19.0, P < 0.001¹	45.9 ± 18.8, P < 0.001¹	48.0 ± 22.6, P < 0.001¹	56.0 ± 22.9, P < 0.001¹	51.3 ± 29.8, P = 0.001¹	51.7 ± 23.1, P = 0.001¹
PSF-12 score	33.18 ± 9.41	35.9 ± 8.4, P = 0.100	39.7 ± 7.9, P = 0.001¹	42.9 ± 10.4, P < 0.001¹	44.5 ± 10.9, P = 0.007¹	44.6 ± 9.3, P = 0.001¹	43.4 ± 13.1, P = 0.003¹
MSF-12 score	47.98 ± 9.94	55.7 ± 7.8, P = 0.002¹	48.5 ± 9.8, P = 0.467	50.0 ± 9.3, P = 0.405	50.9 ± 10.5, P = 0.200	50 ± 9.5, P = 0.139	56.7 ± 4.8, P = 0.001¹

¹Denotes statistical significance.

VAS: Visual analogue scale; IKDC: International Knee Documentation Committee; KOOS: Knee Injury and Osteoarthritis Outcome Subscale Scores; SF-12: Short Form-12; PSF-12: Physical Short Form-12 MSF-12: Mental Short Form-12; PreOp: Pre-operative.

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Citation: Desai B, Willard JG, Assid E, Hall C, Renshaw A, Schoofs E, Wilder JH, Hatcher L, Tupler R, Jones D. Missouri osteochondral preservation system transplantation: Outcome scores from 24 months to 60+ months. World J Orthop 2026; 17(9): 114039
URL: https://www.wjgnet.com/2218-5836/full/v17/i9/114039.htm
DOI: https://dx.doi.org/10.5312/wjo.114039

Desai B, Willard JG, Assid E, Hall C, Renshaw A, Schoofs E, Wilder JH, Hatcher L, Tupler R, Jones D. Missouri osteochondral preservation system transplantation: Outcome scores from 24 months to 60+ months. World J Orthop 2026; 17(9): 114039 [DOI: 10.5312/wjo.114039]

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