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Retrospective Cohort Study
Copyright: ©Author(s) 2026.
World J Orthop. Aug 18, 2026; 17(8): 122060
Published online Aug 18, 2026. doi: 10.5312/wjo.122060
Table 2 Patient demographics, comorbidities and surgical details by protocol, n (%)/mean ± SD
Demographics/comorbidities
Usual care (n = 208)
Opioid-sparing protocol (n = 82)
P value
Age (years)55.6 ± 13.554.0 ± 13.40.358
BMI (kg/m2)28.8 ± 4.928.3 ± 5.50.524
Gender0.569
Male92 (44.2)42 (51.2)
Female116 (55.8)40 (48.8)
Race0.8541
Black21 (10.1)6 (7.3)
White175 (84.1)71 (86.6)
Other12 (5.8)5 (6.1)
CCI score21.0 (0.0-2.0)1.0 (0.0-2.0)0.562
ASA score0.169
112 (5.8)9 (11.0)
2137 (65.9)56 (68.3)
359 (28.4)17 (20.7)
Depression/anxiety90 (43.3)41 (50.0)0.365
Chronic opioid use8 (3.8)7 (8.5)0.1381
Current smoker21 (10.1)13 (15.9)0.242
Former smoker63 (30.3)17 (20.7)0.135
Surgical details
Surgery type
Anterior cervical fusion49 (23.6)20 (24.4)1
Lumbar laminectomy/discectomy131 (63.0)59 (72.0)0.190
Posterior lumbar fusion28 (13.5)3 (3.7)0.0191
Operative levels0.856
1174 (83.7)70 (85.4)
234 (16.3)12 (14.6)


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