Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis

doi:10.5312/wjo.121157

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 7

This Article

(22)

(17)

(0)

(214)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Orthopedics

ISSN

2218-5836

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. Jul 18, 2026; 17(7): 121157
Published online Jul 18, 2026. doi: 10.5312/wjo.121157

Table 1 Comparative analysis of biomechanical outcomes by groups, mean ± SD/median (interquartile range)

	Control		Celecoxib		Efficacy of celecoxib: Operated control vs operated celecoxib	Control (operated vs non-operated)	Celecoxib (operated vs non-operated)
	Non-operated limb	Operated limb	Non-operated limb	Operated limb		Control (operated vs non-operated)	Celecoxib (operated vs non-operated)
PEA-2 (º)	136.7 ± 29.5	107.5 ± 11.6	122.9 ± 28.6	124.5 ± 28.6	P = 0.259	P = 0.065	P = 0.891
PEA-4 (º)	153.4 ± 24.0	112.8 ± 35.2	145.0 ± 35.5	136.5 ± 29.4	P = 0.129	P = 0.011	P = 0.566
PEA-8 (º)	159.1 ± 22.6	123.7 ± 34.0	167.1 ± 37.0	162.4 ± 34.8	P = 0.026	P = 0.044	P = 0.769
PEA-failure (º)	204.6 (33.6)	138.1 (33.4)	229.4 (17)	222.5 (24.6)	P = 0.015	P = 0.043	P = 0.247
Failure torque (N·cm)	18.4 ± 8.9	21.2 ± 8.9)	32.3 ± 9.9	38.8 ± 11.1	P = 0.002	P = 0.588	P = 0.187
Elastic torque (N·cm)	13.1 ± 8.9	19.8 ± 8.9	29.1 ± 11.7	34.7 ± 11.6	P = 0.009	P = 0.063	P = 0.294
Stiffness (N·cm/º)	0.3 (0.4)	0.5 (0.4)	0.6 (0.4)	0.8 (0.8)	P = 0.637	P = 0.293	P = 0.579
Energy (N·cm·º)	1.1 (1.4)	0.9 (2.4)	2.2 (1.8)	3.7 (2.2)	P = 0.050	P = 0.463	P = 0.089

PEA: Passive extension angle.

Full Size Table

Citation: Palacios-Díaz L, Diez Sánchez B, González-García Á, Pena-Burgos EM, Pozo-Kreilinger JJ, Carrascal-Morillo MT, Bustos A, Sanchez-Urgelles P, Antuña S, Barco R. Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis. World J Orthop 2026; 17(7): 121157
URL: https://www.wjgnet.com/2218-5836/full/v17/i7/121157.htm
DOI: https://dx.doi.org/10.5312/wjo.121157

Palacios-Díaz L, Diez Sánchez B, González-García Á, Pena-Burgos EM, Pozo-Kreilinger JJ, Carrascal-Morillo MT, Bustos A, Sanchez-Urgelles P, Antuña S, Barco R. Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis. World J Orthop 2026; 17(7): 121157 [DOI: 10.5312/wjo.121157]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.