MiR 26a as a stage-dependent biomarker and therapeutic regulator of inflammation in knee osteoarthritis

doi:10.5312/wjo.120195

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. Jul 18, 2026; 17(7): 120195
Published online Jul 18, 2026. doi: 10.5312/wjo.120195

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Figure 3 Correlation heat map of 26a2 and 26a5 vs target genes. A: 26a2; B: 26a5. Heat map depicting the Pearson correlation coefficients between miRNA-26a2 and 26a5 and their target genes (NF-κB, Cox, MMP13, and NOS) among different grades of osteoarthritis individuals: The scale on the right-hand side indicates the correlation coefficient values. Values closer to ± 1 show stronger correlations, while values near 0 imply a weak or non-linear relationship. Red shades denote positive correlations. Blue shades denote negative correlations.

Citation: Gunamala V, Hari R, Jeyaraman N, Nallakumarasamy A, Muthu S, Jeyaraman M. MiR 26a as a stage-dependent biomarker and therapeutic regulator of inflammation in knee osteoarthritis. World J Orthop 2026; 17(7): 120195
URL: https://www.wjgnet.com/2218-5836/full/v17/i7/120195.htm
DOI: https://dx.doi.org/10.5312/wjo.120195

Gunamala V, Hari R, Jeyaraman N, Nallakumarasamy A, Muthu S, Jeyaraman M. MiR 26a as a stage-dependent biomarker and therapeutic regulator of inflammation in knee osteoarthritis. World J Orthop 2026; 17(7): 120195 [DOI: 10.5312/wjo.120195]

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