Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures

doi:10.5312/wjo.v17.i5.116844

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. May 18, 2026; 17(5): 116844
Published online May 18, 2026. doi: 10.5312/wjo.v17.i5.116844

Table 7 Comparison of adverse reactions and remedial indicators between the two patient groups, median (25^th-75^th percentiles), n (%)

Group	Remedial indicator		Adverse reactions
Group	Sufentanil dose	Number of compressions	PONV	Shivering	Excessive sleepiness
Control (n = 40)	81.0 (70.0-91.0)	11.0 (8.0-16.0)	15 (37.5)	7 (17.5)	16 (40.0)
LB (n = 40)	68.0 (66.0-78.0)^a	8.0 (5.0-9.0)^a	6 (15.0)	3 (7.5)	3 (7.5)
z/χ² value	-2.855	-3.393	5.230	1.829	11.665
P value	0.004	0.001	0.041	0.311	0.001

^aP < 0.05.

LB: Liposomal bupivacaine; PONV: Postoperative nausea and vomiting.

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Citation: Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844
URL: https://www.wjgnet.com/2218-5836/full/v17/i5/116844.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i5.116844

Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844 [DOI: 10.5312/wjo.v17.i5.116844]

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