Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures

doi:10.5312/wjo.v17.i5.116844

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. May 18, 2026; 17(5): 116844
Published online May 18, 2026. doi: 10.5312/wjo.v17.i5.116844

Table 5 Comparison of mini-mental state examination scores of the two patient groups at each time point, median (25^th-75^th percentiles)

Indicator	Group	T0	T1	T6	T7
MMSE (score)	Control (n = 40)	27.0 (26.0-28.0)	27.0 (26.0-28.0)	24.0 (23.0-25.0)	25.0 (24.0-25.0)
MMSE (score)	LB (n = 40)	27.0 (26.0-28.0)	28.0 (28.0-28.0)^a	27.0 (26.0-280)^a	27.0 (27.0-28.0)^a
t value		-2.567	-3.624	-6.275	-5.662
P value		0.631	0.000	0.000	0.000

^aP < 0.05.

Mini-mental state examination score ranges from 0 to 30. LB: Liposomal bupivacaine; MMSE: Mini-mental state examination; T0: 1 day before surgery; T1: Upon entering the operating room; T6: 3 days after surgery; T7: 7 days after surgery.

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Citation: Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844
URL: https://www.wjgnet.com/2218-5836/full/v17/i5/116844.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i5.116844

Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844 [DOI: 10.5312/wjo.v17.i5.116844]

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