Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures

doi:10.5312/wjo.v17.i5.116844

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World Journal of Orthopedics

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2218-5836

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. May 18, 2026; 17(5): 116844
Published online May 18, 2026. doi: 10.5312/wjo.v17.i5.116844

Table 2 Comparison of mean arterial pressure and heart rate at each time point between the two patient groups, median (25^th-75^th percentiles)

	Group	T0	T1	T2	T3
MAP (mmHg)	Control (n = 40)	116.0 (103.0-126.0)	102.0 (88.0-113.0)	91.0 (76.0-101.0)	101.0 (93.0-112.0)
MAP (mmHg)	LB (n = 40)	110.0 (92.0-127.0)	92.0 (87.0-96.0)^a	91.0 (80.0-101.0)	99.0 (90.0-100.0)^a
z value		-1.261	-2.628	-0.284	-2.082
P value		0.207	0.009	0.776	0.037
Heart rate	Control (n = 40)	90.0 (79.0-108.0)	87.0 (76.0-87.0)	78.0 (71.0-85.0)	85.0 (78.0-92.0)
Heart rate	LB (n = 40)	85.0 (79.0-94.0)	73 (70.0-76.0)^a	76.0 (70.0-83.0)	74 (66.0-80.0)^a
z value		-1.136	-4.797	-0.809	-5.109
P value		0.256	0.000	0.419	0.000

^aP < 0.05.

LB: Liposomal bupivacaine; MAP: Mean arterial pressure; T0: 1 day before surgery; T1: Upon entering the operating room; T2: 6 hours after surgery; T3: 12 hours after surgery.

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Citation: Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844
URL: https://www.wjgnet.com/2218-5836/full/v17/i5/116844.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i5.116844

Liu H, Jia T, Shuai SC, Zhao JB. Effect of liposomal bupivacaine for iliac fascia block on postoperative cognitive dysfunction in patients with femoral neck fractures. World J Orthop 2026; 17(5): 116844 [DOI: 10.5312/wjo.v17.i5.116844]

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