Prognostic factors for patients undergoing surgery for femur metastases following systemic treatment

doi:10.5312/wjo.v17.i5.116525

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. May 18, 2026; 17(5): 116525
Published online May 18, 2026. doi: 10.5312/wjo.v17.i5.116525

Table 1 Patient clinical characteristics

Characteristic	n
Age at bone metastasis diagnosis	Median 73.5 (range, 50-87)
Sex
Male	11
Female	13
Type of cancer
Lung cancer
With molecularly targeted therapy	1
Without molecularly targeted therapy	3
Breast cancer
Hormone dependent	5
Hormone independent	2
Prostate cancer
Hormone dependent	2
Hormone independent	1
Colorectal cancer	2
Esophageal cancer	1
Hepatocellular carcinoma	1
Kidney cancer	1
Bladder cancer	1
Multiple myeloma	3
Malignant lymphoma	1
Surgical method
Osteosynthesis	17
Artificial head replacement	7
Systemic treatment before surgery
Hormone therapy	6
Anticancer drugs and/or molecularly targeted drugs	18
Visceral metastasis
Yes	14
No	10
Number of bone metastases
1	6
Multiple	18
Pathological fractures
Yes	6
No	18
Systemic treatment after surgery
Yes	14
No	10

Full Size Table

Citation: Ishibashi Y, Nakazato K, Tachibana N, Yu J, Ugawa S, Asanuma Y, Kusunoki Y, Hasebe S, Takahashi T, Hara N. Prognostic factors for patients undergoing surgery for femur metastases following systemic treatment. World J Orthop 2026; 17(5): 116525
URL: https://www.wjgnet.com/2218-5836/full/v17/i5/116525.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i5.116525

Ishibashi Y, Nakazato K, Tachibana N, Yu J, Ugawa S, Asanuma Y, Kusunoki Y, Hasebe S, Takahashi T, Hara N. Prognostic factors for patients undergoing surgery for femur metastases following systemic treatment. World J Orthop 2026; 17(5): 116525 [DOI: 10.5312/wjo.v17.i5.116525]

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