Comparison of neurohormone and callus volume formation in long bone fractures associated with or without traumatic brain injury

doi:10.5312/wjo.v17.i5.116068

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. May 18, 2026; 17(5): 116068
Published online May 18, 2026. doi: 10.5312/wjo.v17.i5.116068

Table 6 Multivariate regression: Predictors of callus volume at 6 weeks

Variable	Coefficient	P value	Significant
GH 7 days	0.38	0.002	Yes
PTH 7 days	0.31	0.011	Yes
IL-6 7 days	0.41	0.001	Yes
TBI status	0.49	0.0005	Yes
Age	-0.02	0.21	No
Sex	0.06	0.33	No

GH: Growth hormone; PTH: Parathyroid hormone; IL-6: Interleukin-6; TBI: Traumatic brain injury.

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Citation: Mounisamy P, Singh H, Vairappan B, Rajasekar G, Chandrashekar S, Jeyaraman N, Jeyaraman M. Comparison of neurohormone and callus volume formation in long bone fractures associated with or without traumatic brain injury. World J Orthop 2026; 17(5): 116068
URL: https://www.wjgnet.com/2218-5836/full/v17/i5/116068.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i5.116068

Mounisamy P, Singh H, Vairappan B, Rajasekar G, Chandrashekar S, Jeyaraman N, Jeyaraman M. Comparison of neurohormone and callus volume formation in long bone fractures associated with or without traumatic brain injury. World J Orthop 2026; 17(5): 116068 [DOI: 10.5312/wjo.v17.i5.116068]

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