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Systematic Reviews
Copyright: ©Author(s) 2026.
World J Orthop. Apr 18, 2026; 17(4): 115881
Published online Apr 18, 2026. doi: 10.5312/wjo.v17.i4.115881
Table 1 Basic studies, patients’, and fracture characteristics, mean ± SD/n (%)
Ref.CountryStudy typeTotal number of patients included in the studyNumber of patients who had aTKAAgeGender
ComorbiditiesConcomitant knee OAEvaluating abnormal bone profile (author’s remarks)Fracture details
Male
Female
Trauma mechanism
Fracture location
Classification
Abdelbadie et al[28], 2020EgyptRetrospective cohort study43 (22 aTKA vs 21 ORIF)2267.1 (60-73)81486.4% of the patients [diabetes (36.4%), HT (35.5%), IHD (27.3%), CLD (4.5%)] 5 (22.7) NA [9 (40.9) patients were on bisphosphonates]14 high energy (6 falls, 2 RTA, 6 MCA)TPFsSchatzker type II (7, 31.8%), Schatzker type III (8, 36.4%), Schatzker type IV (7, 31.8%)
Asikin et al[29], 2022MalaysiaCase report117510NRNRNAHigh energy (MCA)TPFsSchatzker type V
Boureau et al[30], 2015FranceCase series21 (10 distal femur fractures and 11 proximal tibia fractures)1179 (68-96)83NR (ASA III: 6, ASA II: 5)NRNA (all patients showed radiologic osteopenia)NRTPFs5 Schatzker II, 2 Schatzker IV, 3 Schatzker V and 1 Schatzker VI
Haufe et al[31], 2016GermanyCase series303078.4 (59-93)1317NRNRNANRTPFsAO/OTA: Type B (13), type C fracture (17); 6: 41B2, 5: 41B3, 5: 41C1, 7: 41C2, and 7: 41C3
Hesmerg et al[32], 2024NetherlandsRetrospective cohort study68 (34 matched pairs: 12 aTKA vs 22 late TKA)1269.0 (65.3-79.5) (median)111NR [ASA I/II: 8 (66.7%)]NRNATraffic accident 2 (16.7%), fall from height 4 (33.3%), blunt trauma 1 (8.3%); other 4 (33.3%), unknown 1 (8.3%)TPFsSchatzker II (2, 16.7%). Type III (3, 25.0%). Type IV (1, 8.3%). Type V (4, 33.3%). Type VI (2, 16.7%)
Huang et al[33], 2016ChinaCase series6669.5 (58-78)33NRNRNAAll were high energy (traffic accidents and falls from height)TPFs4 Schatzker V and 2 Schatzker VI
Kadakia et al[34], 2007United KingdomCase report118501NR: Patient’s chest radiograph showed evidence of previous scarringNRNA (operative findings revealed that the bone was mushy and porotic)Low energy (fell on the knee from standing height)TPFsSchatzker type IV
Mirzatolooei et al[35], 2021IranCase series111154.3 ± 4.7011RA [all patients were on anti-RA agents, especially corticosteroid (prednisolone) for at least 5 years (range: 5-8)]11 (100)It was evaluated by DXA scan 6 months before the surgery; the mean T-score was -3.8 ± 0.7All were low energyPTFsNR
Sabatini et al[36], 2023ItalyCase series111176 ± 6 (65-84)47NR11 (100)NA8 low energy (simple fall), 3 high energy (car accident)TPFsAO/OTA: Type B (8), type C fracture (3); one (41B1), 5 (41B3), 2 (41B2), 1 (41C1), 2 (41C2)
Sarzaeem et al[37], 2017IranCase series303067.6 ± 4.2 (61-78)1911NR23 (76.7)NA (7 had osteoporosis)14 high energyTPFs + PTFsAO/OTA: Type A (5), type B (22), type C fracture (3); 5 (41A), 22 (41 B), 3 (41 C)
Sivasubramanian et al[38], 2016SingaporeCase series3370.4 (59.2-79.0)12NR3 (100)NA (poor bone stock)All high energyTPFs2 Schatzker II and one Schatzker III
Tapper et al[39], 2020FinlandCase series222274 ± 12 (53-88)616NR5 (22.7)NA (deficient bone stock)13 low energy, 9 high energyTPFs6 Schatzker II, 7 Schatzker III, 2 Schatzker IV, 5 Schatzker V, 2 Schatzker VI
Vermeire and Scheerlinck[40], 2010BelgiumCase series121273 (58-81)39NR5 (41.7)NA6 low energy, 6 high energyTPFsAO/OTA: Type B (9), type C fracture (3); one 41-B1, 8: 41-B3, 3: 41-C3
Wui et al[41], 2020MalaysiaCross-sectional study10 (6 distal femur, 2 proximal tibial, and 2 combined distal femur and proximal tibial fractures)264 (55-76)11NRNRNA (poor bone quality)NRTPFsAO/OTA: Type C fracture (2); one 41C3.1, one 41C3.3


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