Obesity and total ankle arthroplasty: Contraindication or consideration

doi:10.5312/wjo.v17.i3.115288

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World Journal of Orthopedics

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2218-5836

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World J Orthop. Mar 18, 2026; 17(3): 115288
Published online Mar 18, 2026. doi: 10.5312/wjo.v17.i3.115288

Table 2 Complication rates in total ankle replacement related to obesity

Ref.	Overall rate			Infection/wound complications			90-day readmission			ARF
Ref.	Obese	Non-obese	P value	Obese	Non-obese	P value	Obese	Non-obese	P value	Obese	Non-obese	P value
Gross et al[20], 2016	11%	16.5%	0.196	0.5%	2.26%	0.431	NR	NR	NR	NR	NR	NR
Bouchard et al[21], 2015	Similar	Similar	0.48	0%	2.1%	NS	NR	NR	NR	NR	NR	NR
Cunningham et al[16], 2018	NR	NR	NR	1.82%	3.85%	0.28	1.32%	4.1%	0.99	NR	NR	NR
Cottom et al[13], 2019	11.4%	18.9%	0.308	NR	NR	NS	NR	NR	NR	NR	NR	NR
Kim et al[6], 2023	21.8%	27%	0.126	0.4%	1.3%	0.274	NR	NR	NR	NR	NR	NR
Best et al[17], 2022	3.8%	2.5%	0.530¹	NR	NR	NR	NR	NR	NR	NR	NR	NR
Kwon et al[18], 2023	Non-associated with BMI		NR	0.6%		Non-associated with BMI	1.4%		Non-associated with BMI²	NR	NR	NR
Bakaes et al[10], 2024	2.6%	12%	0.436	7.8%	15.7%	NS	NR	NR	NR	0%	0%	> 0.05
Werner et al[12], 2015	Significantly increased risk for obese patients		< 0.001	4.7%	2.2%	< 0.001	NR	NR	NR	NR	NR	NR
Sambandam et al[14], 2023	NR	NR	NR	NR	NR	NR	NR	NR	NR	15	22	0.002³
Sy et al[15], 2025	NR	NR	NR	NR	NR	NR	BMI > 30 is associated with non-home discharge^a^,⁴		< 0.01	NR	NR	NR

^aP < 0.01.

¹Odds ratio = 1.5, 95% confidence interval: 0.40-5.8.

²Odds ratio = 0.95, 95% confidence interval: 0.87-1.03.

³Odds ratio = 2.70, 95% confidence interval: 1.4-5.22.

⁴Odds ratio = 1.93, 95% confidence interval: 1.29-2.89.

NR: Non-reported; NS: Non-significant; ARF: Acute renal failure; BMI: Body mass index.

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Citation: Pinto I, Konstantinou P, Kostretzis L, Nikolaides AP, Ditsiou AZ, Chrysanthou C, Kapetanakis S, Ditsios K. Obesity and total ankle arthroplasty: Contraindication or consideration. World J Orthop 2026; 17(3): 115288
URL: https://www.wjgnet.com/2218-5836/full/v17/i3/115288.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i3.115288

Pinto I, Konstantinou P, Kostretzis L, Nikolaides AP, Ditsiou AZ, Chrysanthou C, Kapetanakis S, Ditsios K. Obesity and total ankle arthroplasty: Contraindication or consideration. World J Orthop 2026; 17(3): 115288 [DOI: 10.5312/wjo.v17.i3.115288]

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