Value of “true” leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Feb 18, 2026; 17(2): 113667
Published online Feb 18, 2026. doi: 10.5312/wjo.v17.i2.113667

Table 1 Preoperative international consensus meeting criteria scoring system

	Cut off	Score¹
Serum CRP	> 1 mg/dL	2
Serum D-dimer	> 860 ng/mL	2
Serum ESR	> 30 mm/hour	1
WBC (synovial)	> 3000 cells/μL	3
Alpha-defensin (synovial)	Qualitative	3
Leukocyte esterase (synovial)	Qualitative	3
Neutrophil (synovial, %)	> 80%	2
CRP (synovial)	> 6.9 mg/L	1

¹Adapted from Parvizi et al[11].

CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; WBC: White blood cell.

Citation: Sweeney BM, Sadhwani S, Edwards T, Kelly M. Value of “true” leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting. World J Orthop 2026; 17(2): 113667
URL: https://www.wjgnet.com/2218-5836/full/v17/i2/113667.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i2.113667

Sweeney BM, Sadhwani S, Edwards T, Kelly M. Value of “true” leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting. World J Orthop 2026; 17(2): 113667 [PMID: 41695735 DOI: 10.5312/wjo.v17.i2.113667]

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