Factors associated with aseptic loosening after primary total hip arthroplasty: A systematic review and meta-analysis

Table 5 Summary of meta-analysed factors for the aseptic loosening after primary total hip arthroplasty

Factors	Pooled OR	LL 95%CI	UL 95%CI	P value	I2	Effects model
Age	0.998	0.911	1.093	0.964	86.033	R
Gender (male)	1.232	1.039	1.460	0.016	87.230	R
BMI	1.116	1.059	1.175	< 0.001	91.057	R
CCI	1.378	1.182	1.606	< 0.001	88.230	R
Lifestyle	2.198	1.048	4.611	0.037	99.140	R
Diagnosis	1.162	1.009	1.338	0.037	61.546	R
Anatomy	1.082	0.876	1.336	0.466	82.582	R
Race	0.445	0.302	0.655	< 0.001	0.000	F
Genetype	0.723	0.617	0.849	< 0.001	0.000	F
Surgical skills	1.048	1.021	1.075	< 0.001	12.78	F
Prosthesis	1.497	1.203	1.864	< 0.001	89.958	R

I² was defined as the proportion of heterogeneity not due to chance or random error. OR: Odds ratio; LL: Lower limit; UL: Upper limit; BMI: Body mass index; CCI: Charlson Comorbidity Index; R: Random-effects model was performed; F: Fixed-effects model was performed.