Factors associated with aseptic loosening after primary total hip arthroplasty: A systematic review and meta-analysis

Table 1 The general characteristics of the included studies

Ref.	Country	Study design	Follow-up (years)	Participations	AL (n)	AL rates, %	Age (years)	NOS
Davis et al[61], 2020	United Kingdom	Cohort study	≥ 7.5	290770	1260	0.43	73.17	7
Amstutz et al[49], 2015	United States	Case-control study	8.58	1375	27	1.96	46.5	7
Benson et al[35], 2022	Denmark	Cohort study	4.4 (1.1-5.9)	53605	479	0.89	NA	7
Bordini et al[15], 2007	Italy	Cohort study	≥ 6	4750	134	2.82	NA	6
Jud et al[42], 2024	Switzerland	Cohort study	NA	2459	14	0.56	63.8 ± 12.7 (18-92)	7
Wagener et al[62], 2024	Germany	Cohort study	2-10	255	255	NA	73	7
Budin et al[34], 2024	United States	Cohort study	2	32811	721	2.19	69.1 ± 8.3	8
Magruder et al[32], 2024	United States	Cohort study	≤ 2	11025	160	1.45	NA	6
Aro et al[13], 2012	Finland	Cohort study	2	39	NA	NA	61.5 (41-78)	6
Electricwala et al[23], 2016	United States	Cohort study	8.7 ± 8.1	257	NA	NA	67 ± 13	7
Münger et al[14], 2006	Sweden	Case-control study	5.3 ± 3.1	50534	725	1.43	63 ± 9.5	8
Layson et al[29], 2024	United States	Cohort study	2	55601	NA	1.91	68-72	7
Clauss et al[58], 2013	Switzerland	Cohort study	≥ 16	156	139	NA	NA	7
Khatod et al[43], 2014	United States	Cohort study	2.2 (1.2-5.1)	36834	635	1.72	65.5 ± 11.7	8
Stelmach et al[45], 2015	Germany	Cohort study	NA	465	234	NA	52.80 ± 12.8	7
Wedemeyer et al[44], 2009	Germany	Cohort study	7.17-8.41	87	87	NA	69.31 ± 10.27	7
Lee et al[56], 2024	China	Cohort study	≥ 1	1995	4	0.2	61.9 ± 13.8	7
Lunn et al[33], 2005	Ireland	Case-control study	5.7 (2-11)	217	101	NA	67.6 ± 9.6	6
Halawi et al[26], 2016	United States	Cohort study	7.6 ± 2.56	426	28	6.57	46.9 ± 7.1	7
Boyer et al[19], 2019	France	Cohort study	5.5	30733	NA	NA	NA	6

AL: Aseptic loosening; NOS: Newcastle Ottawa Scale; NA: Not available.