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Retrospective Cohort Study
©The Author(s) 2025.
World J Orthop. Sep 18, 2025; 16(9): 110386
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.110386
Table 2 Revision rate and reason for revision rates for Novation, Alteon, and aggregate antioxidant groups, n (%)
Revisions
Novation (n = 461)

Alteon (n = 989)

Aggregate antioxidant (n = 39964)
Novation vs aggregate, P value
Alteon vs aggregate, P value
All-cause4 (0.87)18 (1.82)986 (2.47)0.020.23
Fracture (including periprosthetic fracture)2 (0.43)6 (0.61)247 (0.62)0.990.99
Infection0 (0.00)6 (0.61)205 (0.51)0.180.86
Aseptic loosening0 (0.00)2 (0.20)116 (0.29)0.650.99
Instability0 (0.00)3 (0.30)248 (0.62)0.120.30
Mechanical complications0 (0.00)2 (0.20)101 (0.25)0.630.33
Hematoma or wound complications0 (0.00)1 (0.10)24 (0.06)0.990.46
Wear0 (0.00)0 (0.00)3 (0.01)0.990.99
Pain0 (0.00)2 (0.20)80 (0.20)0.990.99
Revisions for all other reasons2 (0.43)1 (0.10)229 (0.57)0.190.05


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