Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights

Figure 4 Traditional Chinese medicine suppress osteoarthritis-related inflammation by inhibiting the Janus kinase/signal transducer and activator of transcription 3, nuclear factor kappa B, reactive oxygen speciesand NOD-like receptor 3 inflammatory signaling pathways. TNF: Tumor necrosis factor; NF-κB: Nuclear factor kappa B; ROS: Reactive oxygen species; TCM: Traditional Chinese medicine; IL: Interleukin; NLRP3: NOD-like receptor 3; STAT: Signal transducer and activator of transcription; JAK: Janus kinase.