Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights

doi:10.5312/wjo.v16.i9.108629

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Sep 18, 2025; 16(9): 108629
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.108629

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Figure 3 Traditional Chinese medicine alleviate inflammatory bone destruction in ankylosing spondylitis through nuclear factor erythroid/reactive oxygen species/nuclear factor kappa B axis and interleukin-17A signaling pathway. TH17: T helper-17; TNF-α: Tumor necrosis factor α; IL: Interleukin; IκBα: IkappaB α; NF-κB: Nuclear factor kappa B; Nrf2: Nuclear factor erythroid 2-related factor 2; ROS: Reactive oxygen species; TCM: Traditional Chinese medicine; MMP14: Matrix metalloproteinase 14; TAK1: Transforming growth factor beta-activated kinase 1; MAPK: Mitogen-activated protein kinase.

Citation: Lu JS, Yang M, Han ZG, Song CY, Sarbay N, Wang KY. Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights. World J Orthop 2025; 16(9): 108629
URL: https://www.wjgnet.com/2218-5836/full/v16/i9/108629.htm
DOI: https://dx.doi.org/10.5312/wjo.v16.i9.108629

Lu JS, Yang M, Han ZG, Song CY, Sarbay N, Wang KY. Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights. World J Orthop 2025; 16(9): 108629 [PMID: 40979151 DOI: 10.5312/wjo.v16.i9.108629]

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