Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights

Figure 2 Traditional Chinese medicine reduce the synovial inflammation of rheumatoid arthritis through phosphatidylinositol 3-kinase/protein kinase B, Janus kinase/signal transducer and activator of transcription 3 and nuclear factor kappa B signaling pathways. RA: Rheumatoid arthritis; TNF-α: Tumor necrosis factor α; IL: Interleukin; NF-κB: Nuclear factor kappa B; IκB: IkappaB; SLPI: Secretory leukocyte protease inhibitor; PI3K/AKT: Phosphatidylinositol 3-kinase/protein kinase B; STAT3: Signal transducer and activator of transcription 3.