Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review

doi:10.5312/wjo.v13.i9.825

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World Journal of Orthopedics

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2218-5836

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World J Orthop. Sep 18, 2022; 13(9): 825-836
Published online Sep 18, 2022. doi: 10.5312/wjo.v13.i9.825

Table 3 Fragility index values for each outcome for included randomized controlled trials

First author (last name)	Comparison	Delayed union/ Nonunion	Iatrogenic radial nerve palsy	Infection	Malunion	Shoulder Impingement	Elbow Stiffness	All complications	Secondary surgeries
Kim	ORPO (LCP) vs MIPO	0	0	0	0	NA	NA	0	0
Esmailiejah	ORPO (DCP) vs MIPO	0	0	0	0	NA	NA	0	0
Fan	ORPO (LCP) vs IMN	0	0	NA	NA	NA	NA	0	NA
Hadhoud	ORPO (LCP) vs MIPO	0	0	0	NA	NA	NA	0	NA
Wali	ORPO (DCP) vs IMN	0	0	0	NA	0	0	0	0
Benegas	MIPO vs IMN	0	0	0	0	0	NA	0	0
Lian	MIPO vs IMN	0	0	0	0	1	0	4	NA
Li	ORPO (LCP) vs IMN	0	0	0	2	NA	NA	0	NA
Iqbal	ORPO (DCP) vs IMN	0	0	0	NA	0	NA	0	0
Singisetti	ORPO (DCP) vs IMN	0	0	0	NA	0	0	0	0
Putti	ORPO (DCP) vs IMN	0	0	0	NA	0	NA	0	0
Changulani	ORPO (DCP) vs IMN	0	0	0	NA	1	NA	0	0
Kesemenli	ORPO (DCP) vs IMN	0	1	0	NA	0	NA	0	0
McCormack	ORPO (DCP) vs IMN	0	0	0	0	2	NA	6	1
Chapman	ORPO (DCP) vs IMN	0	0	0	0	2	1	0	0

ORPO: Open reduction and plate osteosynthesis; DCP: Dynamic compression plate; LCP: Locking compression plate; IMN: Intramedullary nail; MIPO: Minimally invasive plate osteosynthesis.

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Citation: Morris SC, Gowd AK, Agarwalla A, Phipatanakul WP, Amin NH, Liu JN. Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review. World J Orthop 2022; 13(9): 825-836
URL: https://www.wjgnet.com/2218-5836/full/v13/i9/825.htm
DOI: https://dx.doi.org/10.5312/wjo.v13.i9.825

Morris SC, Gowd AK, Agarwalla A, Phipatanakul WP, Amin NH, Liu JN. Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review. World J Orthop 2022; 13(9): 825-836 [PMID: 36189338 DOI: 10.5312/wjo.v13.i9.825]

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