Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review

doi:10.5312/wjo.v13.i9.825

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World Journal of Orthopedics

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2218-5836

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Systematic Reviews

World J Orthop. Sep 18, 2022; 13(9): 825-836
Published online Sep 18, 2022. doi: 10.5312/wjo.v13.i9.825

Table 1 Included randomized controlled trials with characteristics

First author (last name)	Journal	Year	Comparison	Patients enrolled	Patients lost to follow up	Final study, n	JADAD score	Power analysis
Kim	J Orthop Trauma	2015	ORPO (LCP) vs MIPO	72	4	68	3	Yes
Esmailiejah	Trauma Mon	2015	ORPO (DCP) vs MIPO	68	3	65	3	No
Fan	Orthopedics	2015	ORPO (LCP) vs IMN	60	0	60	2	Yes
Hadhoud	Menoufia Medical Journal	2015	ORPO (LCP) vs MIPO	30	0	30	2	No
Wali	Strategies Trauma Limb Reconstr	2014	ORPO (DCP) vs IMN	50	0	50	2	No
Benegas	J Shoulder Elbow Surg	2014	MIPO vs IMN	41	1	40	3	Yes
Lian	Orthopedics	2013	MIPO vs IMN	56	9	47	3	No
Li	J Shoulder Elbow Surg	2011	ORPO (LCP) vs IMN	50	5	45	3	Yes
Iqbal	Annals of King Edward Medical University	2011	ORPO (DCP) vs IMN	40	0	40	3	No
Singisetti	Int Orthop	2010	ORPO (DCP) vs IMN	45	9	36	1	No
Putti	J Orthop Surg (Hong Kong)	2009	ORPO (DCP) vs IMN	34	0	34	2	No
Changulani	Int Orthop	2007	ORPO (DCP) vs IMN	47	2	45	3	No
Kesemenli	Acta Orthop Traumatol Turc	2003	ORPO (DCP) vs IMN	60	0	60	2	No
McCormack	J Bone Joint Surg (Br)	2000	ORPO (DCP) vs IMN	44	3	41	2	No
Chapman	J Orthop Trauma	2000	ORPO (DCP) vs IMN	89	5	84	3	No

ORPO: Open reduction and plate osteosynthesis; DCP: Dynamic compression plate; LCP: Locking compression plate; IMN: Intramedullary nail; MIPO: Minimally invasive plate osteosynthesis.

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Citation: Morris SC, Gowd AK, Agarwalla A, Phipatanakul WP, Amin NH, Liu JN. Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review. World J Orthop 2022; 13(9): 825-836
URL: https://www.wjgnet.com/2218-5836/full/v13/i9/825.htm
DOI: https://dx.doi.org/10.5312/wjo.v13.i9.825

Morris SC, Gowd AK, Agarwalla A, Phipatanakul WP, Amin NH, Liu JN. Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review. World J Orthop 2022; 13(9): 825-836 [PMID: 36189338 DOI: 10.5312/wjo.v13.i9.825]

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