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Copyright ©The Author(s) 2021.
World J Orthop. Feb 18, 2021; 12(2): 61-68
Published online Feb 18, 2021. doi: 10.5312/wjo.v12.i2.61
Figure 1
Figure 1 Schematic diagram indicating how a vicious cycle can occur between equinus contracture and foot ulceration in patients with diabetes. TGF-β: Transforming growth factor β; AGEs: Advanced glycation end-products; RAAS: Renin angiotensin aldosterone system; ECM: Extracellular matrix.