Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model

Figure 4 Graph representing the comparative level of total IgG antibody measured in mice immunized with Survivin (+ Mycobacterium indicus pranii), LHRH(6leu)LTB (+ Mycobacterium indicus pranii) and combination of Survivin and LHRH(6leu)-LTB (+ Mycobacterium indicus pranii). The serum was collected pre tumor challenge (Day -7), on tumor challenge (Day 0) and at the end of the study (Day 38). The total IgG titer was determined against respective antigens in each group. Groups of mice receiving Survivin alone and combination were checked for anti-Survivin antibody titers. Similarly, anti-LHRH titres were checked in mice in groups corresponding to LHRH(6leu)-LTB alone and combination. LHRH: Luteinizing hormone-releasing hormone.