Copyright
©2014 Baishideng Publishing Group Inc.
World J Clin Oncol. Dec 10, 2014; 5(5): 874-882
Published online Dec 10, 2014. doi: 10.5306/wjco.v5.i5.874
Published online Dec 10, 2014. doi: 10.5306/wjco.v5.i5.874
Figure 1 Base-excision repair.
Simplified schematic representation of the short-patch base-excision repair pathway showing the key steps and main proteins involved in the repair of a damaged DNA base. Adapted from Costa et al[8]. OGG1: 8-oxoguanine DNA glycosylase 1; APE1: Apurinic/apyrimidinic endonuclease 1; PARP-1: Poly (ADP-ribose) polymerase-1; XRCC1: X-ray repair cross complementing group 1; Polβ: DNA polymerase-β; LIGIII: DNA ligase III.
- Citation: Patrono C, Sterpone S, Testa A, Cozzi R. Polymorphisms in base excision repair genes: Breast cancer risk and individual radiosensitivity. World J Clin Oncol 2014; 5(5): 874-882
- URL: https://www.wjgnet.com/2218-4333/full/v5/i5/874.htm
- DOI: https://dx.doi.org/10.5306/wjco.v5.i5.874