Squamous cell carcinoma of the skin: Emerging need for novel biomarkers

doi:10.5306/wjco.v4.i4.85

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Editorial

World J Clin Oncol. Nov 10, 2013; 4(4): 85-90
Published online Nov 10, 2013. doi: 10.5306/wjco.v4.i4.85

Table 2 Risk factors for recurrence and metastasis of cutaneous squamous cell carcinoma

Variable	Approximate relative risk¹
Variable	Recurrence	Metastasis
Rapid tumor growth	-	-
Tumor size > 2 cm	2	2
Tumor location (lip/ear)	2	3
Immunosuppression	-	2
Previous radiotherapy	-	-
Previously treated cSCC	3	4
RDEB -associated cSCC	-	-
Tumor depth > 4 mm	2	5
Poor differentiation	2	3
Acantholytic features	-	-
Spindle-cell features	-	-
Perineural invasion	5	5

Originated from Alam et al[1], with permission.

¹A relative risk of 1 is defined as the likelihood of recurrence or metastasis of a small primary cutaneous squamous cell carcinoma (cSCC). Dashes indicate an association with increased risk, but of which there are insufficient data to estimate the relative risk. RDEB: Recessive dystrophic epidermolysis bullosa.

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Citation: Kivisaari A, Kähäri VM. Squamous cell carcinoma of the skin: Emerging need for novel biomarkers. World J Clin Oncol 2013; 4(4): 85-90
URL: https://www.wjgnet.com/2218-4333/full/v4/i4/85.htm
DOI: https://dx.doi.org/10.5306/wjco.v4.i4.85

Kivisaari A, Kähäri VM. Squamous cell carcinoma of the skin: Emerging need for novel biomarkers. World J Clin Oncol 2013; 4(4): 85-90 [PMID: 24926428 DOI: 10.5306/wjco.v4.i4.85]

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