Combination therapy reduces transarterial chemoembolization resistance in advanced hepatocellular carcinoma

Table 2 Univariate and multivariate analysis of transarterial chemoembolization resistance

Characteristics	Univariate logistic regression analysis			Multivariate logistic regression analysis
	OR	CI	P value	OR	CI	P value
Age	0.98	0.97-1	0.128	-	-	-
Female	1.15	0.59-2.24	0.687	-	-	-
Comorbid hepatitis B	1.06	0.56-2.01	0.858	-	-	-
AFP ≥ 400 μg/L	2.07	1.34-3.19	0.001	1.92	1.42-2.95	0.06
Primary tumor size	1.01	1.01-1.02	< 0.001	1.01	1-1.02	0.001
Number of multiple tumors	1.96	1.21-3.18	0.006	-	-	-
Tumor capsule	0.18	0.11-0.29	< 0.001	0.29	0.17-0.48	0.002
Tumor thrombus	4.52	2.74-7.47	0.03	-	-	-
Bilobar distribution of tumor	2.46	1.59-3.8	< 0.001	2.13	1.3-3.48	0.003
Child-Pugh grade B	2.25	1.1-4.62	0.027	2.14	1.23-4.21	0.07
BCLC-B	2.56	0.92-7.14	0.073	-	-	-
BCLC-C	6.9	2.39-19.92	0.052	-	-	-

AFP: Alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer; OR: Odds ratio; CI: Confidence interval.