Modified scoring model incorporating waist-hip ratio for predicting advanced colorectal neoplasia

Table 6 Validity of the newly developed score model and comparison with Asia-Pacific Colorectal Screening model and modified Asia-Pacific Colorectal Screening model, n (%)

Validation cohort (risk score model of this study) (age, male, smoking, and high wait-to-hip ratio)			Validation cohort (according to APCS model) (age, male, smoking, family history of CRC)			Validation cohort (according to modified APCS model) (age, male, smoking, family history of CRC and body mass index )
Risk tier (risk score)	ACN	Relative risk (95%CI)	Risk tier (risk score)	ACN	Relative risk (95%CI)	Risk tier (risk score)	Advanced colorectal neoplasia	Relative risk (95%CI)
LR (0-2)	47 (5.0)	1	LR (0-1)	46 (5.1)	1	LR (0)	15 (4.9)	1
MR (3-4)	75 (10.3)	2.07 (1.46-2.94)	MR (2-3)	81 (10.4)	2.03 (1.48-2.87)	MR (1–2)	86 (7.7)	1.58 (0.93-2.70)
HR (5-7)	39 (17.6)	3.55 (2.38-5.26)	HR (4-7)	34 (16.2)	3.16 (2.09-4.81)	HR (3–6)	60 (12.9)	2.65 (1.53-4.57)
Hosmer-lemeshow goodness-of-fit statistic	0.71		Hosmer-lemeshow goodness-of-fit statistic	0.59		Hosmer-lemeshow goodness-of-fit statistic	0.27
C-statistic	0.66 ± 0.02		C-statistic	0.63 ± 0.02		C-statistic	0.62 ± 0.02

APCS: Asia-Pacific Colorectal Screening model; CRC: Colorectal cancer; HR: High risk; LR: Low risk; MR: Moderate risk.